The US tariff measures triggered panic in the market. The three major US stock indexes opened sharply lower, with the Dow Jones Industrial Average down 3%, the S&P 500 down 3.41%, and the Nasdaq down 4.6%. Large technology stocks led the decline, with Apple falling 8%, Broadcom, Amazon, Tesla, and Nvidia down more than 6%, and Microsoft down nearly 2%. AstraZeneca rose more than 4%, claiming that oral lipid-lowering drugs can reduce "bad cholesterol" by more than 50%.